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Gateway for Cancer Research is one of the only nonprofits that exclusively funds innovative Phase I and Phase II cancer clinical trials for patients of all ages, regardless of cancer type. At the forefront of research and discovery, these early-phase trials are the first step in evaluating new cancer drugs, treatments, and therapies.
Results 11-18 of 18
Head/Neck Cancer
Novel Use of Cytokine-Induced, Memory-Like Natural Killer Cells in Combination with Ipilimumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Novel Use of Cytokine-Induced, Memory-Like Natural Killer Cells in Combination with Ipilimumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (Phase I) Summary: This clinical trial is examining the novel use of manufactured, personalized cytokine-induced, memory-like natural killer cells (CIML NK cells) to improve immune response against squamous cell […]
Rizwan Romee, MD
Dana-Farber Cancer Institute
Solid Tumors
Novel Use of Brigatinib in Patients with Advanced Solid Tumors with ALK or ROS1 Alterations
Novel Use of Brigatinib in Patients with Advanced Solid Tumors with ALK or ROS1 Alterations (Phase II) Summary: Dr. Roychowdhury and team are examining the use of Brigatinib, a chemotherapy drug that is in pill form, for solid tumors with a rare genetic mutation. This trial is using telemedicine to recruit and onboard patients, ensuring […]
Sameek Roychowdhury, MD, PhD
The Ohio State University
Brain Cancer
Multicenter efficacy study of BLZ-100 tumor paint in pediatric tumors of the central nervous system
Multicenter efficacy study of BLZ-100 tumor paint in pediatric tumors of the central nervous system Brain tumors are the leading cause of death in children. Those who survive the surgeries that excise tumor tissue often suffer a decreased quality of life. It is important to remove as little healthy brain tissue as possible. Surgeons usually […]
Sarah Leary, MD, MS
Seattle Children's
Lung Cancer
Identification of Predictive Biomarkers to Prevent Pneumonitis in Patients with Non-Small Cell Lung Cancer Who are Receiving Immunotherapy
Identification of Predictive Biomarkers to Prevent Pneumonitis in Patients with Non-Small Cell Lung Cancer Who are Receiving Immunotherapy (Phase II) Summary: Immunotherapy has produced durable clinical responses in non-small cell lung cancer (NSCLC) and is the standard of care for these patients. However, severe adverse effects (SAE), such as lung inflammation and pneumonitis can occur in […]
Ajay Sheshadri, MD
The University of Texas MD Anderson Cancer Center
Pancreatic Cancer
GM-CSF Secreting Allogeneic Pancreatic Cancer Vaccine and a PD-1 Pembrolizumab for the Treatment of Patients with Adenocarcinoma
A Phase II Study of a GM-CSF Secreting Allogeneic Pancreatic Cancer Vaccine in Combination with a PD-1 Blockade Antibody (Pembrolizumab) for the Treatment of Patients with Locally Advanced Adenocarcinoma of the Pancreas Locally advanced pancreatic adenocarcinoma (LAPC) is an aggressive and fatal disease. It is usually inoperable because of its proximity to vital blood vessels […]
Lei Zheng, MD, PhD
Johns Hopkins University School of Medicine
Blood Cancer
A Phase II controlled study of microbiome and stem cell transplantation medical home care compared to standard hospital care
Phase II: A controlled study of microbiome and stem cell transplantation medical home care compared to standard hospital care After a hematopoietic stem cell transplant, which is the treatment of choice for a variety of malignant and non-malignant diseases, the patients are isolated in the hospital because their immune systems are so weak and depleted. […]
Nelson Chao, MD, MBA
Duke University School of Medicine
Pediatric Acute Myeloid Leukemia
Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells in Children and Young Adults with Relapsed/Refractory Acute Myeloid Leukemia
Anti-CD33 CAR T Cells in Children and Young Adults with Relapsed/Refractory Acute Myeloid Leukemia (Phase I/II) Summary: Dr. Devine and team are conducting the first trial in children and young adults examining CAR T cell therapy as a treatment for relapsed or refractory acute myeloid leukemia (AML). CAR T cell therapy is when a patient’s […]
Steven Devine, MD
Be The Match Foundation
All Cancers
Acupuncture for symptom control in hematopoietic stem cell transplantation patients
Acupuncture for symptom control in hematopoietic stem cell transplantation patients: A pilot study This study will precisely evaluate acupuncture’s ability to alleviate the nausea, pain and insomnia which occur with chemotherapy. If acupuncture proves to be beneficial, it would be a welcome alternative to pharmacological interventions. Multiple myeloma patients receive chemotherapy prior to getting stem […]
Gary Deng, MD
Memorial Sloan Kettering Cancer Center
